17297-56-2
17297-56-2
Chemical Structure
Biorobin
Synonym(s): Kaempferol 3-O-robinobioside
- CAS No.: 17297-56-2
- Formula:C27H30O15
- Molecular Weight:594.52
IUPAC Name: 5,7-dihydroxy-2-(4-hydroxyphenyl)-3-(((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-((((2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)methyl)tetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-4-one
InChIKey: RTATXGUCZHCSNG-KYGWAIEOSA-N
SMILES: O=C(C(O[C@@H]1O[C@@H]([C@@H]([C@@H]([C@H]1O)O)O)CO[C@H]2[C@@H]([C@@H]([C@H]([C@@H](O2)C)O)O)O)=C(C3=CC=C(C=C3)O)OC4=CC(O)=C5)C4=C5O
Biological Activity: Biorobin (Kaempferol 3-O-robinobioside), a flavonoid, significantly inhibits the human lymphocyte proliferation in vitro[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Biorobin | 99.94% | Biorobin (Kaempferol 3-O-robinobioside), a flavonoid, significantly inhibits the human lymphocyte proliferation in vitro. | ||||||||||||||||||||
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Kaempferol 3-neohesperidoside (Standard) | ≥98% | Kaempferol 3-neohesperidoside (Kaempferol 3-O-neohesperidoside) Standard is the analytical standard of Kaempferol 3-neohesperidoside (HY-107207). This product is intended for research and analytical applications. Kaempferol 3-neohesperidoside (Kaempferol 3-O-neohesperidoside) is a flavonoid. Kaempferol 3-neohesperidoside mimics insulin action via the PI3K/PKC pathway, significantly promoting glucose uptake and increasing muscle glycogen content in rat soleus muscles. Kaempferol 3-neohesperidoside also exhibits anti-glycation activity. Kaempferol 3-neohesperidoside binds to albumin through hydrogen bonding and hydrophobic interactions, and inhibits the formation of advanced glycation end products. Kaempferol 3-neohesperidoside can be used in studies of diabetes and its related complications. | ||||||||||||||||||||
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Ternatumoside II | Ternatumoside II is a flavonoid glycoside that can be isolated from R. crenulata. Ternatumoside II can stimulate IFN-γ expression. Ternatumoside II has radical-scavenging activities (IC50s: 260.5 μM and 320.2 μM for DPPH and ABTS). | |||||||||||||||||||||
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Rutin | 98.09% | Rutin (Rutoside) is a flavonoid found in many plants and shows a wide range of biological activities including anti-inflammatory, antidiabetic, antioxidant, neuroprotective, nephroprotective, hepatoprotective and reducing Aβ oligomer activities. Rutin is also a CBR1 inhibitor, which can cross the blood brain barrier. Rutin attenuates vancomycin-induced renal tubular cell apoptosis via suppression of apoptosis, mitochondrial dysfunction, and oxidative stress. | ||||||||||||||||||||
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Kaempferol-3-O-glucorhamnoside | 99.64% | Kaempferol-3-O-glucorhamnoside is a flavonoid compound. Kaempferol-3-O-glucorhamnoside can be extracted from T. chinense Turcz. Kaempferol-3-O-glucorhamnoside inhibits the phosphorylation of NF-κB and MAPK kinases. Kaempferol-3-O-glucorhamnoside suppresses the expression of cytokines (TNF-α, IL-6, IL-1β and PGE2) and reduces ROS levels. Kaempferol-3-O-glucorhamnoside ameliorates pulmonary edema and alleviates oxidative stress in the lungs and cells of mice exposed to Klebsiella pneumoniae. Kaempferol-3-O-glucorhamnoside possesses anti-inflammatory properties. Kaempferol-3-O-glucorhamnoside can be used in studies related to Klebsiella pneumoniae infection (pneumonia). | ||||||||||||||||||||
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Multiflorin B | 98.51% | Multiflorin B (compound 5) is a kind of kaempferol glycoside. Multiflorin B can be isolated from the root of the fern Neocheiropteris palmatopedata. Multiflorin B inhibits nitric oxide production at a concentration of 20 μg/ml with an inhibition of 52%. | ||||||||||||||||||||
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Nicotiflorin | 99.85% | Nicotiflorin is a flavonoid glycoside extracted from a traditional Chinese medicine Carthamus tinctorius. Nicotiflorin shows potent antiglycation activity and neuroprotection effects. | ||||||||||||||||||||
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Kaempferol 3-O-gentiobioside | 99.47% | Kaempferol 3-O-gentiobioside is an orally active flavonoid, with a Ka value of 57 µM against human NOTCH1 and an IC50 value of 50 μM against α-glucosidase. Kaempferol 3-O-gentiobioside inhibits the NOTCH signaling pathway. It downregulates the expression of TLR4 and NLRP3, and suppresses the activation and nuclear translocation of NF-κB. Kaempferol 3-O-gentiobioside inhibits the expression of MUC5AC, reduces nitrite and ROS levels, and attenuates excessive mucus secretion. It exhibits antibacterial activity, reducing the formation and growth of MRSA biofilms. Kaempferol 3-O-gentiobioside blocks the TGF-β/ALK5/Smad signaling pathway and inhibits epithelial-mesenchymal transition. It suppresses the proliferation, migration, invasion and metastatic growth of tumor cells. Kaempferol 3-O-gentiobioside alleviates airway inflammation and mucus hypersecretion in mice with allergic asthma. It reduces the volume of ovarian cancer xenografts in mice. Kaempferol 3-O-gentiobioside can be used in research related to allergic asthma, diabetes, MRSA infection, breast cancer, gastric cancer and ovarian cancer. | ||||||||||||||||||||
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Quercetin 3-O-robinobioside | 99.80% | Quercetin 3-O-robinobioside can be isolated from the leaves of Strychnos variabilis. | ||||||||||||||||||||
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Kaempferol 3-rungioside | Kaempferol 3-rungioside is a glycoside derivative of Kaempferol (HY-14590). | |||||||||||||||||||||
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5,6,7,4'-Tetrahydroxyflavonol 3-O-rutinoside | 5,6,7,4'-Tetrahydroxyflavonol 3-O-rutinoside is a natural antioxidant flavonoid glycoside. | |||||||||||||||||||||
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