174254-13-8
Chemical Structure
Biricodar dicitrate
Synonym(s): VX 710-3
- CAS No.: 174254-13-8
- Formula:C46H57N3O21
- Molecular Weight:987.95
IUPAC Name: 1,7-di(pyridin-3-yl)heptan-4-yl (S)-1-(2-oxo-2-(3,4,5-trimethoxyphenyl)acetyl)piperidine-2-carboxylate bis(2-hydroxypropane-1,2,3-tricarboxylate)
InChIKey: VDMKJSJJXQDICL-ZXVJYWQYSA-N
SMILES: O=C([C@H]1N(C(C(C2=CC(OC)=C(OC)C(OC)=C2)=O)=O)CCCC1)OC(CCCC3=CC=CN=C3)CCCC4=CC=CN=C4.O=C(CC(C(O)=O)(O)CC(O)=O)O.O=C(CC(C(O)=O)(O)CC(O)=O)O
Biological Activity: Biricodar dicitrate (VX 710-3) is the dicitrate salt form of Biricodar (HY-13574A). Biricodar dicitrate is an inhibitor for P-glycoprotein and multidrug resistance-associated protein 1 (MRP-1), which increases the accumulation of chemotherapy drugs within cancer cells and shows effective chemosensitizing activity in multidrug resistant cells[1].
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Biricodar dicitrate | Biricodar dicitrate (VX 710-3) is the dicitrate salt form of Biricodar (HY-13574A). Biricodar dicitrate is an inhibitor for P-glycoprotein and multidrug resistance-associated protein 1 (MRP-1), which increases the accumulation of chemotherapy drugs within cancer cells and shows effective chemosensitizing activity in multidrug resistant cells. | |||||||||||||||||||||
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