17702-88-4
17702-88-4
Chemical Structure
2-Aminodecanoic acid
- CAS No.: 17702-88-4
- Formula:C10H21NO2
- Molecular Weight:187.28
IUPAC Name: 2-aminodecanoic acid
InChIKey: JINGUCXQUOKWKH-UHFFFAOYSA-N
SMILES: O=C(O)C(N)CCCCCCCC
Biological Activity: 2-Aminodecanoic acid is a lipophilic α-amino acid with an aliphatic side chain of 10 carbon atoms. 2-Aminodecanoic acid modifies the N-terminus of endogenous opioid peptide endomorphin-1 to enhance metabolic stability and membrane permeability. 2-Aminodecanoic acid can be used for the research of neuropathic pain[1][2].
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2-Aminodecanoic acid | 2-Aminodecanoic acid is a lipophilic α-amino acid with an aliphatic side chain of 10 carbon atoms. 2-Aminodecanoic acid modifies the N-terminus of endogenous opioid peptide endomorphin-1 to enhance metabolic stability and membrane permeability. 2-Aminodecanoic acid can be used for the research of neuropathic pain. | |||||||||||||||||||||
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References
- [1]. Staab CA, et al. Medium-chain fatty acids and glutathione derivatives as inhibitors of S-nitrosoglutathione reduction mediated by alcohol dehydrogenase 3. Chem Biol Interact. 2009;180(1):113-118. [Content Brief]
- [2]. Varamini P, et al. Lipo-endomorphin-1 derivatives with systemic activity against neuropathic pain without producing constipation. PLoS One. 2012;7(8):e41909. [Content Brief]
