1776055-05-0
1776055-05-0
Chemical Structure
ML230
Synonym(s): CID44640177; SID 88095709
- CAS No.: 1776055-05-0
- Formula:C25H21N5O3
- Molecular Weight:439.47
IUPAC Name: (4-(5-(furan-2-yl)-2-phenylpyrazolo[1,5-a]pyrimidin-7-yl)piperazin-1-yl)(furan-3-yl)methanone
InChIKey: LRPGMVPQQLBMNE-UHFFFAOYSA-N
SMILES: O=C(C1=COC=C1)N2CCN(C3=CC(C4=CC=CO4)=NC5=CC(C6=CC=CC=C6)=NN53)CC2
Biological Activity: ML230 (CID44640177; SID 88095709) is a selective inhibitor of ATP-binding cassette (ABC) transporter ABCG2, and 36-fold selective for ABCG2 over ABCB1 with EC50s values of 0.13 μM and 4.65 μM, respectively[1].
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ML230 | 99.65% | ML230 (CID44640177; SID 88095709) is a selective inhibitor of ATP-binding cassette (ABC) transporter ABCG2, and 36-fold selective for ABCG2 over ABCB1 with EC50s values of 0.13 μM and 4.65 μM, respectively. | ||||||||||||||||||||
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ML230 (Standard) | ≥98% | ML230 (Standard) is the analytical standard of ML230 (HY-111678). This product is intended for research and analytical applications. ML230 (CID44640177; SID 88095709) is a selective inhibitor of ATP-binding cassette (ABC) transporter ABCG2, and 36-fold selective for ABCG2 over ABCB1 with EC50s values of 0.13 μM and 4.65 μM, respectively. | ||||||||||||||||||||
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