1776055-29-8
1776055-29-8
Chemical Structure
Efflux inhibitor-1
- CAS No.: 1776055-29-8
- Formula:C28H25N5O3
- Molecular Weight:479.53
IUPAC Name: furan-3-yl(4-(2-(2-methoxyphenyl)-5-phenylpyrazolo[1,5-a]pyrimidin-7-yl)piperazin-1-yl)methanone
InChIKey: SFNWNSAJWDYPJC-UHFFFAOYSA-N
SMILES: COC1=CC=CC=C1C2=NN(C(N3CCN(C(C4=COC=C4)=O)CC3)=CC(C5=CC=CC=C5)=N6)C6=C2
Biological Activity: Efflux inhibitor-1 is a pyrazolo[1,5-a]pyrimidine-based efflux inhibitor that inhibits the efflux activity of ABCG2 (IC50 = 0.45 µM) and ABCB1 (IC50 = 2.17 µM). Efflux inhibitor-1 can be used in research related to drug-resistant ovarian cancer and leukemia[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Efflux inhibitor-1 | 99.74% | Efflux inhibitor-1 is a pyrazolo[1,5-a]pyrimidine-based efflux inhibitor that inhibits the efflux activity of ABCG2 (IC50 = 0.45 µM) and ABCB1 (IC50 = 2.17 µM). Efflux inhibitor-1 can be used in research related to drug-resistant ovarian cancer and leukemia. | ||||||||||||||||||||
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