1788896-33-2
1788896-33-2
Chemical Structure
NL-103
- CAS No.: 1788896-33-2
- Formula:C26H27Cl2N5O4
- Molecular Weight:544.43
IUPAC Name: N-(4-chloro-3-(3-chlorobenzamido)phenyl)-6-((7-(hydroxyamino)-7-oxoheptyl)amino)nicotinamide
InChIKey: RJWLMMYFBDEKDT-UHFFFAOYSA-N
SMILES: O=C(C1=CN=C(NCCCCCCC(NO)=O)C=C1)NC2=CC=C(C(NC(C3=CC(Cl)=CC=C3)=O)=C2)Cl
Biological Activity: NL-103 is an inhibitor of histone deacetylases (HDACs) and Hedgehog, with the IC50 values of 21.3 nM, 57 nM, 74 nM, and 680 nM for HDAC1, HDAC2, HDAC3, and HDAC6, respectively. NL-103 can downregulate the expression of Gli2. NL-103 can be used in anti-cancer research[1].
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NL-103 | NL-103 is an inhibitor of histone deacetylases (HDACs) and Hedgehog, with the IC50 values of 21.3 nM, 57 nM, 74 nM, and 680 nM for HDAC1, HDAC2, HDAC3, and HDAC6, respectively. NL-103 can downregulate the expression of Gli2. NL-103 can be used in anti-cancer research. | |||||||||||||||||||||
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