1795137-84-6
Chemical Structure
1-Linoleoyl Glycerol-d5
Synonym(s): 1-Linoleoyl-rac-glycerol-d5; 1-Monolinolein-d5
- CAS No.: 1795137-84-6
- Formula:C21H33D5O4
- Molecular Weight:359.55
InChIKey: WECGLUPZRHILCT-HRFNPRCSSA-N
SMILES: OC([2H])(C([2H])(C([2H])(OC(CCCCCCC/C=C\C/C=C\CCCCC)=O)[2H])O)[2H]
Biological Activity: 1-Linoleoyl Glycerol-d5 (1-Linoleoyl-rac-glycerol-d5; 1-Monolinolein-d5) is the deuterium labeled 1-Linoleoyl Glycerol (HY-111346). 1-Linoleoyl glycerol is a LpPLA2 inhibitor. 1-Linoleoyl glycerol acts as a precursor for synthesizing various functional lipids, such as phospholipids. 1-Linoleoyl glycerol mitigates inflammation induced by Apolipoprotein CIII (reduction of IL-6)[1][2][3].
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1-Linoleoyl Glycerol-d5 | 1-Linoleoyl Glycerol-d5 (1-Linoleoyl-rac-glycerol-d5; 1-Monolinolein-d5) is the deuterium labeled 1-Linoleoyl Glycerol (HY-111346). 1-Linoleoyl glycerol is a LpPLA2 inhibitor. 1-Linoleoyl glycerol acts as a precursor for synthesizing various functional lipids, such as phospholipids. 1-Linoleoyl glycerol mitigates inflammation induced by Apolipoprotein CIII (reduction of IL-6). | |||||||||||||||||||||
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1-Linoleoyl Glycerol (Standard) | ≥98% | 1-Linoleoyl Glycerol (Standard) is the analytical standard of 1-Linoleoyl Glycerol. This product is intended for research and analytical applications. 1-Linoleoyl glycerol is a LpPLA2 inhibitor. 1-Linoleoyl glycerol acts as a precursor for synthesizing various functional lipids, such as phospholipids. 1-Linoleoyl glycerol mitigates inflammation induced by Apolipoprotein CIII (reduction of IL-6). | ||||||||||||||||||||
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1-Linoleoyl Glycerol | 99.52% | 1-Linoleoyl glycerol is a LpPLA2 inhibitor. 1-Linoleoyl glycerol acts as a precursor for synthesizing various functional lipids, such as phospholipids. 1-Linoleoyl glycerol mitigates inflammation induced by Apolipoprotein CIII (reduction of IL-6). | ||||||||||||||||||||
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1-Monopalmitolein | 99.0% | 1-Palmitoleoyl glycerol is a biologically active monoacylglycerol. It increases daunomycin accumulation, shown to inhibit P-glycoprotein in Caco-2 cells. 1-Palmitoleoyl glycerol induces thymocyte apoptosis. | ||||||||||||||||||||
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7.9 MAG | 7.9 MAG is a non-monoolein lipid and acts as a detergent for crystallization. | |||||||||||||||||||||
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8.8 MAG | 8.8 MAG acts as a detergent for crystallization. | |||||||||||||||||||||
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8.7 MAG | 8.7 MAG acts as a detergent for crystallization. | |||||||||||||||||||||
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Mono-10(Z)-heptadecenoin | Mono-10(Z)-heptadecenoin is a monoglyceride. | |||||||||||||||||||||
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Mono-13(Z),16(Z)-docosadienoin | Mono-13(Z),16(Z)-docosadienoin is an acylglycerol. | |||||||||||||||||||||
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9(E)-Monohexadecenoin | 9(E)-Monohexadecenoin is an acylglycerol. | |||||||||||||||||||||
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8(Z),11(Z),14(Z)-Monoeicosatrienoin | 8(Z),11(Z),14(Z)-Monoeicosatrienoin is an acylglycerol. | |||||||||||||||||||||
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1-Linoleoyl-(2S)-glycerol | 1-Linoleoyl-(2S)-glycerol is a lipid with a structure similar to that of linoleic acid. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. | |||||||||||||||||||||
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1-Linoleoyl-3-chloropropanediol | 1-Linoleoyl-3-chloropropanediol (Rac-1-Linoleoyl-3-chloropropanediol) is a lipid product. | |||||||||||||||||||||
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References
- [1]. Archambault AS, et al. Biosynthesis of the Novel Endogenous 15-Lipoxygenase Metabolites N-13-Hydroxy-octodecadienoyl-ethanolamine and 13-Hydroxy-octodecadienoyl-glycerol by Human Neutrophils and Eosinophils. Cells. 2021 Sep 5;10(9):2322. [Content Brief]
- [2]. Duan H, et al. Dose-dependent effect of Dendrobium officinale polysaccharide on anti-aging in Caenorhabditis elegans: A metabolomics analysis focused on lipid and nucleotide metabolism regulation. Food Bioscience, 2024, 61: 104615.
- [3]. Lee WS, et al. Lp-PLA2 inhibitory activities of fatty acid glycerols isolated from Saururus chinensis roots. Bioorg Med Chem Lett. 2005 Aug 1;15(15):3573-5. [Content Brief]