1795786-02-5
1795786-02-5
Chemical Structure
(R)-Linezolid-d3
Synonym(s): (R)-PNU-100766-d3
- CAS No.: 1795786-02-5
- Formula:C16H17D3FN3O4
- Molecular Weight:340.36
IUPAC Name: (R)-N-((3-(3-fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl)acetamide-2,2,2-d3
InChIKey: TYZROVQLWOKYKF-JJMJVRKHSA-N
SMILES: O=C1N(C[C@@H](CNC(C([2H])([2H])[2H])=O)O1)C2=CC(F)=C(C=C2)N3CCOCC3
Biological Activity: (R)-Linezolid-d3 ((R)-PNU-100766-d3) is the deuterium labeled (R)-Linezolid. (R)-Linezolid is an impurity of Linezolid (PNU-100766). Linezolid, the first member of the class of oxazolidinone synthetic antibiotic, acts by inhibiting the initiation of bacterial protein synthesis[1][2].
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(R)-Linezolid-d3 | (R)-Linezolid-d3 ((R)-PNU-100766-d3) is the deuterium labeled (R)-Linezolid. (R)-Linezolid is an impurity of Linezolid (PNU-100766). Linezolid, the first member of the class of oxazolidinone synthetic antibiotic, acts by inhibiting the initiation of bacterial protein synthesis. | |||||||||||||||||||||
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(R)-Linezolid (Standard) | ≥98% | (R)-Linezolid (Standard) is the analytical standard of (R)-Linezolid. This product is intended for research and analytical applications. (R)-Linezolid is an impurity of Linezolid (PNU-100766). Linezolid, the first member of the class of oxazolidinone synthetic antibiotic, acts by inhibiting the initiation of bacterial protein synthesis. | ||||||||||||||||||||
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(R)-Linezolid | 99.18% | (R)-Linezolid is an impurity of Linezolid (PNU-100766). Linezolid, the first member of the class of oxazolidinone synthetic antibiotic, acts by inhibiting the initiation of bacterial protein synthesis. | ||||||||||||||||||||
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References
- [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
- [2]. Bednarek E, et al. NMR and molecular modeling study, as complementary techniques to capillary electrophoresis method to elucidate the separation mechanism of linezolid enantiomers. J Chromatogr A. 2008 Jun 6;1193(1-2):164-71. [Content Brief]
