1799330-15-6
Chemical Structure
Galeflaprit
Synonym(s): LXE408
- CAS No.: 1799330-15-6
- Formula:C23H18FN7O2
- Molecular Weight:443.43
IUPAC Name: N-(4-fluoro-3-(6-(3-methylpyridin-2-yl)-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)phenyl)-2,4-dimethyloxazole-5-carboxamide
InChIKey: GNVVPYCWVLCWKV-UHFFFAOYSA-N
SMILES: O=C(C1=C(C)N=C(C)O1)NC2=CC=C(F)C(C3=NN4C=C(C5=NC=CC=C5C)C=NC4=N3)=C2
Biological Activity: Galeflaprit (LXE408) is an orally active, non-competitive and kinetoplastid-selective proteasome inhibitor. Galeflaprit has an IC50 of 0.04 μM for L. donovani proteasome and an EC50 of 0.04 μM for L. donovani. Galeflaprit has a low propensity to cross the blood brain barrier. Galeflaprit has the potential for visceral leishmaniasis (VL) research[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Galeflaprit | 99.75% | Galeflaprit (LXE408) is an orally active, non-competitive and kinetoplastid-selective proteasome inhibitor. Galeflaprit has an IC50 of 0.04 μM for L. donovani proteasome and an EC50 of 0.04 μM for L. donovani. Galeflaprit has a low propensity to cross the blood brain barrier. Galeflaprit has the potential for visceral leishmaniasis (VL) research. | ||||||||||||||||||||
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