179953-98-1
Chemical Structure
AAPDNRETF
- CAS No.: 179953-98-1
- Formula:C43H65N13O16
- Molecular Weight:1020.05
InChIKey: RBPLVQPLURORME-SGNWOGLDSA-N
SMILES: O=C(N[C@@H](C)C(N1[C@@H](CCC1)C(N[C@@H](CC(O)=O)C(N[C@@H](CC(N)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCC(O)=O)C(N[C@@H]([C@H](O)C)C(N[C@@H](CC2=CC=CC=C2)C(O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](C)N
Biological Activity: AAPDNRETF is a dominant minor histocompatibility antigen presented by H-2Db， which antigen is expressed in C57BL/6 mice and can be recognized by T cells from C3H.SW mice, thereby inducing a strong immune response. AAPDNRETF can induce graft-versus-host disease in irradiated C57BL/6 recipient mice via transfer of sensitized T lymphocytes. AAPDNRETF is applicable to the research of graft-versus-host disease[1].
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AAPDNRETF | AAPDNRETF is a dominant minor histocompatibility antigen presented by H-2Db， which antigen is expressed in C57BL/6 mice and can be recognized by T cells from C3H.SW mice, thereby inducing a strong immune response. AAPDNRETF can induce graft-versus-host disease in irradiated C57BL/6 recipient mice via transfer of sensitized T lymphocytes. AAPDNRETF is applicable to the research of graft-versus-host disease. | |||||||||||||||||||||
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