1801695-56-6
Chemical Structure
Sulfo-Cy3 Azide
- CAS No.: 1801695-56-6
- Formula:C35H46N6O10S3
- Molecular Weight:806.97
IUPAC Name: 2-((E)-3-((E)-1-(6-((3-azidopropyl)amino)-6-oxohexyl)-3,3-dimethyl-5-sulfoindolin-2-ylidene)prop-1-en-1-yl)-3,3-dimethyl-1-(3-sulfopropyl)-3H-indol-1-ium-5-sulfonate
InChIKey: KVKVTWIEKGPCPZ-UHFFFAOYSA-N
SMILES: [N-]=[N+]=NCCCNC(CCCCCN1C2=CC=C(S(=O)(O)=O)C=C2C(C)(C)/C1=C\C=C\C3=[N+](CCCS(=O)(O)=O)C4=C(C3(C)C)C=C(S(=O)([O-])=O)C=C4)=O
Biological Activity: Sulfo-Cy3 Azide is a water-soluble fluorogenic dye containing an azide group, which enables Click Chemistry. Sulfo-Cy3 Azide can be used for the labeling of sensitive molecules such as proteins[1][2]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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Sulfo-Cy3 Azide | 99.57% | Sulfo-Cy3 Azide is a water-soluble fluorogenic dye containing an azide group, which enables Click Chemistry. Sulfo-Cy3 Azide can be used for the labeling of sensitive molecules such as proteins. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups. | ||||||||||||||||||||
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References
- [1]. Luo Q, et al. Dinitroimidazoles as bifunctional bioconjugation reagents for protein functionalization and peptide macrocyclization. Nat Commun. 2019 Jan 11;10(1):142. [Content Brief]
- [2]. Syga Ł, et al. A Trifunctional Linker for Palmitoylation and Peptide and Protein Localization in Biological Membranes. Chembiochem. 2020 May 4;21(9):1320-1328. [Content Brief]
