1803270-60-1
1803270-60-1
Chemical Structure
Frunexian
Synonym(s): EP-7041
- CAS No.: 1803270-60-1
- Formula:C19H26N4O4
- Molecular Weight:374.43
InChIKey: NYPSZHLKEMYZKK-XFJVYGCCSA-N
SMILES: OC([C@@H](N(C1=O)C(N[C@@H](C2CCCCC2)C)=O)[C@H]1CC3=CC=NC(N)=C3)=O
Biological Activity: Frunexian (EP-7041) is a potent and selective FXIa inhibitor. Frunexian produces anticoagulant effects and rapidly restores normal coagulation function. Frunexian can be used in thrombosis research[1][2][3][4].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Frunexian | 97.01% | Frunexian (EP-7041) is a potent and selective FXIa inhibitor. Frunexian produces anticoagulant effects and rapidly restores normal coagulation function. Frunexian can be used in thrombosis research. | ||||||||||||||||||||
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References
- [1]. Vedovati MC, et al. A new strategy for anticoagulation: The factor XI inhibitors. European journal of internal medicine. 2023 Oct;116:8-15.
- [2]. Prakash S, et al. Factor XI/XIa inhibitors for the prevention and treatment of venous and arterial thromboembolism: A narrative review. Vascular medicine (London, England). 2024 Feb;29(1):85-92. [Content Brief]
- [3]. Prisco D, et al. Factor XI Inhibitors: perspectives in primary and secondary prevention of ischemic stroke. Internal and emergency medicine. 2024 Oct;19(7):1807-1819.
- [4]. Zhang JY, et al. Pharmacokinetics, pharmacodynamics, and safety of frunexian in healthy Chinese volunteer adults: A randomized dose-escalation phase I study. Clinical and translational science. 2024 Apr;17(4):e13787. [Content Brief]
