180869-29-8
180869-29-8
Chemical Structure
p38α-IN-10
- CAS No.: 180869-29-8
- Formula:C18H18FN5O
- Molecular Weight:339.37
InChIKey: FEKULGGHHZEMMU-UHFFFAOYSA-N
SMILES: FC1=CC=C(C2=C(C3=CC=NC(N)=N3)N(C4CCOCC4)C=N2)C=C1
Biological Activity: P38α-IN-10 (Compound 8) is an orally active inhibitor of p38α, with an IC₅₀ of 230 nM. P38α-IN-10 has an inhibitory effect on TNF production induced by LPS (HY-D1056). P38α-IN-10 can be used for the study of diseases such as rheumatoid arthritis and septic shock[1].
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p38α-IN-10 | P38α-IN-10 (Compound 8) is an orally active inhibitor of p38α, with an IC₅₀ of 230 nM. P38α-IN-10 has an inhibitory effect on TNF production induced by LPS (HY-D1056). P38α-IN-10 can be used for the study of diseases such as rheumatoid arthritis and septic shock. | |||||||||||||||||||||
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