1809420-72-1
1809420-72-1
Chemical Structure
Resomelagon acetate
Synonym(s): AP1189 acetate
- CAS No.: 1809420-72-1
- Formula:C16H18N6O4
- Molecular Weight:358.35
InChIKey: FIESOFUABUPMMH-WAJHRQJSSA-N
SMILES: N=C(N)N/N=C/C=C/C1=CC=CN1C2=C(C=CC=C2)[N+]([O-])=O.CC(O)=O
Biological Activity: Resomelagon (AP1189) acetate is a potent, orally active melanocortin receptor (MR) agonist about MC1 and MC3. Resomelagon acetate induces ERK1/2 phosphorylation and Ca2+ mobilization. Resomelagon acetate has anti-inflammatory activity. Resomelagon acetate can be used for obesity and chronic inflammation research[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Resomelagon acetate | 99.15% | Resomelagon (AP1189) acetate is a potent, orally active melanocortin receptor (MR) agonist about MC1 and MC3. Resomelagon acetate induces ERK1/2 phosphorylation and Ca2+ mobilization. Resomelagon acetate has anti-inflammatory activity. Resomelagon acetate can be used for obesity and chronic inflammation research. | ||||||||||||||||||||
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References
- [1]. Montero-Melendez T, et, al. Biased agonism as a novel strategy to harness the proresolving properties of melanocortin receptors without eliciting melanogenic effects. J Immunol. 2015 Apr 1;194(7):3381-8. [Content Brief]
- [2]. WHO Drug Information. International Nonproprietary Names for Pharmaceutical.
