1811556-64-5
1811556-64-5
Chemical Structure
TAMRA-FP
- CAS No.: 1811556-64-5
- Formula:C37H47FN3O6P
- Molecular Weight:679.76
InChIKey: JEVJWIYMEMUCFU-UHFFFAOYSA-N
SMILES: O=C(C1=C(C2=C3C=CC(N(C)C)=CC3=[O+]C4=C2C=CC(N(C)C)=C4)C=CC(C(NCCCCCCCCCCP(F)(OCC)=O)=O)=C1)[O-]
Biological Activity: TTAMRA-FP is an activity-based probe for serine hydrolases (Serine Hydrolase) that irreversibly and covalently labels the active-site serine of catalytically active serine hydrolases. TTAMRA-FP can be used for activity-based protein profiling of serine hydrolases and related studies on the activity of osteoarthritis-associated proteases[1][2].
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TAMRA-FP | TTAMRA-FP is an activity-based probe for serine hydrolases (Serine Hydrolase) that irreversibly and covalently labels the active-site serine of catalytically active serine hydrolases. TTAMRA-FP can be used for activity-based protein profiling of serine hydrolases and related studies on the activity of osteoarthritis-associated proteases. | |||||||||||||||||||||
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References
- [1]. Bomgarden RD, et al. Profiling the Serine Hydrolase Superfamily using Activity-based Probes. Thermo Fisher Scientific technical poster.
- [2]. Hines M, et al. Exploiting activity-based probes to identify serine protease activity in osteoarthritis. Osteoarthritis and Cartilage. 2024;32(Suppl):S476. Abstract 692.
