1813561-85-1
1813561-85-1
Chemical Structure
DBCO-Cy3
Synonym(s): DBCO-Sulfo-Cy3
- CAS No.: 1813561-85-1
- Formula:C50H54N4O11S3
- Molecular Weight:983.18
InChIKey: ALLGTQOHAQKUOH-UHFFFAOYSA-N
SMILES: O=S(CCC[N+]1=C(/C=C/C=C2N(CCCCCC(NCCC(N3C4=CC=CC=C4C#CC5=CC=CC=C5C3)=O)=O)C6=C(C=C(S(=O)(O)=O)C=C6)C/2(C)C)C(C)(C)C7=C1C=CC(S(=O)(O)=O)=C7)([O-])=O
Biological Activity: DBCO-Cy3 (DBCO-Sulfo-Cy3) is the derivative of Cyanine3 fluorophore, a pH insensitive from pH (4-10) orange fluorescent dyewith excitation maximum 555 nm and emission maximum of 580nm. DBCO-Cy3 has fast reaction kinetics and good stability, and is productive to use in many standard fluorescent instrumentations. DBCO-Cy3 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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DBCO-Cy3 | 93.92% | DBCO-Cy3 (DBCO-Sulfo-Cy3) is the derivative of Cyanine3 fluorophore, a pH insensitive from pH (4-10) orange fluorescent dyewith excitation maximum 555 nm and emission maximum of 580nm. DBCO-Cy3 has fast reaction kinetics and good stability, and is productive to use in many standard fluorescent instrumentations. DBCO-Cy3 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. | ||||||||||||||||||||
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Sulfo-Cy5 azide | 98.97% | Sulfo-Cy5 azide is a near-infrared fluorescent probe with favorable click chemistry reactivity. Sulfo-Cy5 azide enables fluorescence imaging, tissue and cellular visualization of PD-L1 in tumors, and site-specific modification of anti-PD-L1 antibodies. Sulfo-Cy5 azide has been employed for RNA labeling and imaging. Sulfo-Cy5 azide can be conjugated to targeting agents for fluorescence imaging in atherosclerosis and breast cancer models (Ex/Em = 645/670 nm). | ||||||||||||||||||||
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Trisulfo-Cy3 Methyltetrazine | Trisulfo-Cy3 Methyltetrazine is a click chemistry reagent containing an methyltetrazine group. Methyltetrazine-activated Cy3 probe reacts with TCO-containing compounds via an Inverse-Electron-Demand Diels-Alder reaction to form a stable covalent bond and does not require Cu-catalyst or elevated temperatures. | |||||||||||||||||||||
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Cy5.5 DBCO | Cy5.5 DBCO is a click chemistry reagent containing an cycloalkynes group. Cy5.5 DBCO is a linker of Cyanine5.5 fluorophore. DBCO group enables copper free biocompatible click chemistry with fast reaction kinetics and good stability. | |||||||||||||||||||||
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Sulfo-Cy3-Tetrazine | Sulfo-Cy3-Tetrazine is a membrane-impermeable Fluorescent tetrazine dye. Sulfo-Cy3-Tetrazine performs fluorescent labeling via the tetrazine-TCO click reaction. Sulfo-Cy3-Tetrazine can be used for the study of RSV. | |||||||||||||||||||||
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Cy5-DBCO | 98.93% | Cy5-DBCO (DBCO-Sulfo-Cy5) is a near-infrared (NIR)red fluorescent dye with λabsand λem of 646nm and 670 nm, respectively. Cy5-DBCO (DBCO-Sulfo-Cy5) is not suitable for staining intracellular components of permeabilezed cell, it may exhibits a high background. Cy5-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. | ||||||||||||||||||||
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Sulfo-Cy5-tetrazine | 94.15% | Sulfo Cy5-tetrazine is a tetrazine-coupled Cy5 (HY-D0821) derivative dye with fluorescence properties similar to CY5 (Ex/Em=633/647 nm). Sulfo-Cy5-tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups. | ||||||||||||||||||||
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Cy5 DBCO chloride | Cy5 DBCO chloride is an azide reaction probe and the addition of DBCO molecules allows the imaging of azide-labelled biomolecules by a copper-free "Click Chemistry" reaction. Cy5 DBCO (chloride) is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. | |||||||||||||||||||||
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Cyanine 3 DBCO chloride | Cyanine 3 DBCO chloride is a click chemistry reagent containing an cycloalkynes group. Cyanine 3 DBCO chloride is a linker of Cyanine5.5 fluorophore. DBCO group enables copper free biocompatible click chemistry with fast reaction kinetics and good stability (Ex/Em = 550/570 nm). | |||||||||||||||||||||
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ICG-DBCO | 98.83% | ICG-DBCO is a near-infrared fluorescent click chemistry reagent (Ex/Em = 789/813 nm), composed of Indocyanine green (ICG) (HY-D0711) and dibenzocyclooctyne (DBCO). ICG-DBCO enables copper-free, strain-promoted azide-alkyne cycloaddition (SPAAC) for labeling biomolecules such as antibodies, proteins and peptides, thereby facilitating deep tissue optical imaging. | ||||||||||||||||||||
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Tetra-sulfo-Cy7 DBCO | Tetra-sulfo-Cy7 DBCO is a bright and photostable near-IR probe. The Cy7 DBCO is water-soluble, hydrophilic dye often a reagent of choice for assay where minimal non-specific binding and exceptional brightness is required. The fluorescence of Cy7 DBCO is pH insensitive from pH 4 to pH 10 and produces minimal autofluorescence of biological specimens in this region of the spectrum. Fluorescence of this long-wavelength Cyanine dye is not visible to the human eye but is readily detected by most imaging systems. | |||||||||||||||||||||
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