18145-26-1
18145-26-1
Chemical Structure
Acutumidine
- CAS No.: 18145-26-1
- Formula:C18H22ClNO6
- Molecular Weight:383.82
InChIKey: SBALNGLYQFMKPR-NQTWQHAWSA-N
SMILES: COC([C@@]12[C@](C3)(CCN2)[C@]4([C@@H](C(OC)=CC4=O)O)[C@H](C1)Cl)=C(OC)C3=O
Biological Activity: Acutumidine is a chlorinated alkaloid present in the cultured roots of Menispermum dauricum and Hypserpa nitida Miers. Acutumidine exhibits anti-HBV activity, with an IC50 value of 2.023 mM against hepatitis B virus surface antigen. Acutumidine can be used in studies related to hepatitis B[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Acutumidine | 98.0% | Acutumidine is a chlorinated alkaloid present in the cultured roots of Menispermum dauricum and Hypserpa nitida Miers. Acutumidine exhibits anti-HBV activity, with an IC50 value of 2.023 mM against hepatitis B virus surface antigen. Acutumidine can be used in studies related to hepatitis B. | ||||||||||||||||||||
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References
- [1]. Sugimoto Y, et al. Conversion of dechlorodauricumine into chlorinated alkaloids in Menispermum dauricum root culture. Phytochemistry. 2007 Feb;68(4):493-8.
- [2]. Cheng P, et al. Two new alkaloids and active anti-hepatitis B virus constituents from Hypserpa nitida. Bioorganic & medicinal chemistry letters. 2007 Oct 01;17(19):5316-20. [Content Brief]
