1817791-70-0
1817791-70-0
Chemical Structure
TTK/PLK1-IN-1
- CAS No.: 1817791-70-0
- Formula:C30H33N7O2
- Molecular Weight:523.63
InChIKey: UYPNZGVGCJECJV-UHFFFAOYSA-N
SMILES: O=C(C1=C2CCC3=CN=C(NC4=CC=C(N5CCNCC5)C=C4OC)N=C3N2C=C1)NC6=C(C)C=CC=C6C
Biological Activity: TTK/PLK1-IN-1 (Formula I) is the inhibitor for threonine tyrosine kinase (TTK) and polo-like kinase 1 (PLK1) with IC50 of 7 nM and 72 nM. TTK/PLK1-IN-1 regulates spindle assembly checkpoint (SAC), and exhibits antitumor efficacy against TNBC[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
TTK/PLK1-IN-1 | TTK/PLK1-IN-1 (Formula I) is the inhibitor for threonine tyrosine kinase (TTK) and polo-like kinase 1 (PLK1) with IC50 of 7 nM and 72 nM. TTK/PLK1-IN-1 regulates spindle assembly checkpoint (SAC), and exhibits antitumor efficacy against TNBC. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
