181936-98-1
181936-98-1
Chemical Structure
KC 12291 hydrochloride
- CAS No.: 181936-98-1
- Formula:C22H28ClN3O3S
- Molecular Weight:449.99
IUPAC Name: N-(3,4-dimethoxyphenethyl)-N-methyl-3-((5-phenyl-1,2,4-thiadiazol-3-yl)oxy)propan-1-amine hydrochloride
InChIKey: KIJPRQYBNQKUAU-UHFFFAOYSA-N
SMILES: [H]Cl.CN(CCCOC1=NSC(C2=CC=CC=C2)=N1)CCC3=CC=C(OC)C(OC)=C3
Biological Activity: KC 12291 hydrochloride is an orally active blocker of voltage-gated sodium channel (VGSC). KC 12291 hydrochloride reduces the amplitude of sustained Na+ current to exert antiischemic activity. KC 12291 hydrochloride has significant cardioprotective effect in vitro and in vivo[1].
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KC 12291 hydrochloride | KC 12291 hydrochloride is an orally active blocker of voltage-gated sodium channel (VGSC). KC 12291 hydrochloride reduces the amplitude of sustained Na+ current to exert antiischemic activity. KC 12291 hydrochloride has significant cardioprotective effect in vitro and in vivo. | |||||||||||||||||||||
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