1820763-99-2
Chemical Structure
BCM-599
- CAS No.: 1820763-99-2
- Formula:C14H10Cl2FN3O2
- Molecular Weight:342.15
IUPAC Name: N-(2-((2,6-dichloropyridin-3-yl)amino)-2-oxoethyl)-4-fluorobenzamide
InChIKey: HGXMWUZBYQFEPM-UHFFFAOYSA-N
SMILES: FC1=CC=C(C=C1)C(NCC(NC2=C(N=C(C=C2)Cl)Cl)=O)=O
Biological Activity: BCM-599 is a HBV (hepatitis B virus) capsid assembly inhibitor with the activity of inhibiting HBV capsid assembly. BCM-599 showed an IC50 value of 0.88μM and a CC50 value of 144μM in HepG2.2.15 cells. When used in combination with lamivudine, BCM-599 showed a synergistic inhibitory effect on viral concentration. BCM-599 can be used as an effective combined inhibition option for HBV infection[1].
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BCM-599 | BCM-599 is a HBV (hepatitis B virus) capsid assembly inhibitor with the activity of inhibiting HBV capsid assembly. BCM-599 showed an IC50 value of 0.88μM and a CC50 value of 144μM in HepG2.2.15 cells. When used in combination with lamivudine, BCM-599 showed a synergistic inhibitory effect on viral concentration. BCM-599 can be used as an effective combined inhibition option for HBV infection. | |||||||||||||||||||||
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