1821325-29-4
Chemical Structure
VU6001192
- CAS No.: 1821325-29-4
- Formula:C23H24FN3O3
- Molecular Weight:409.45
IUPAC Name: 6-(((2R,6S)-2,6-dimethylmorpholino)methyl)-1-(4-fluorophenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide
InChIKey: MIESVVLHUFOIOH-GASCZTMLSA-N
SMILES: O=C1C(C(N)=O)=CN(C2=CC=C(CN3C[C@H](O[C@H](C3)C)C)C=C21)C4=CC=C(C=C4)F
Biological Activity: VU6001192 is a potent and selective mGlu2 (metabotropic glutamate receptor 2) negative allosteric modulator. VU6001192 has potent inhibitory activity against the mGlu2 receptor (IC50 = 207 nM), but no activity against the mGlu3 receptor and the other 6 mGlu subtypes. VU6001192 can be used for the research of neurological disease, such as depression[1].
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VU6001192 | VU6001192 is a potent and selective mGlu2 (metabotropic glutamate receptor 2) negative allosteric modulator. VU6001192 has potent inhibitory activity against the mGlu2 receptor (IC50 = 207 nM), but no activity against the mGlu3 receptor and the other 6 mGlu subtypes. VU6001192 can be used for the research of neurological disease, such as depression. | |||||||||||||||||||||
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