1832576-04-1
Chemical Structure
MLT-943
- CAS No.: 1832576-04-1
- Formula:C16H14ClF3N6O2
- Molecular Weight:414.77
IUPAC Name: (S)-1-(2-chloro-7-(1-methoxyethyl)pyrazolo[1,5-a]pyrimidin-6-yl)-3-(2-(trifluoromethyl)pyridin-4-yl)urea
InChIKey: ZMPUACZRXUZAJD-QMMMGPOBSA-N
SMILES: CO[C@H](C1=C(NC(NC2=CC=NC(C(F)(F)F)=C2)=O)C=NC3=CC(Cl)=NN13)C
Biological Activity: MLT-943 is a potent, selective and orally active MALT1 protease inhibitor. MLT-943 inhibits stimulated-IL-2 secretion in PBMC or in whole blood with a similar IC50 across species (0.07-0.09 μM in PBMC, 0.6-0.8 μM in whole blood). MLT-943 has anti-inflammatory activities and can be used for FcgR-mediated inflammation research[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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MLT-943 | 98.93% | MLT-943 is a potent, selective and orally active MALT1 protease inhibitor. MLT-943 inhibits stimulated-IL-2 secretion in PBMC or in whole blood with a similar IC50 across species (0.07-0.09 μM in PBMC, 0.6-0.8 μM in whole blood). MLT-943 has anti-inflammatory activities and can be used for FcgR-mediated inflammation research. | ||||||||||||||||||||
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