18354-85-3
Chemical Structure
N-Isopropylbenzylamine hydrochloride
- CAS No.: 18354-85-3
- Formula:C10H16ClN
- Molecular Weight:185.69
IUPAC Name: 4,6-diethoxy-2-methylpyrimidine
InChIKey: PEIJPMBOGRPKQJ-UHFFFAOYSA-N
SMILES: CC(NCC1=CC=CC=C1)C.Cl
Biological Activity: N-Isopropylbenzylamine hydrochloride is a bulking agent. N-Isopropylbenzylamine hydrochloride induces intracellular nitric oxide (NO) production by targeting neuronal nitric oxide synthase (nNOS), increasing its expression and activation, and causes cell death in neuronal cell lines and inactivation of cytochrome P450, without producing significant toxicity in non-neuronal cells. N-Isopropylbenzylamine hydrochloride can be used for nNOS-related neurotoxicity research[1][2][3][4].
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N-Isopropylbenzylamine hydrochloride | N-Isopropylbenzylamine hydrochloride is a bulking agent. N-Isopropylbenzylamine hydrochloride induces intracellular nitric oxide (NO) production by targeting neuronal nitric oxide synthase (nNOS), increasing its expression and activation, and causes cell death in neuronal cell lines and inactivation of cytochrome P450, without producing significant toxicity in non-neuronal cells. N-Isopropylbenzylamine hydrochloride can be used for nNOS-related neurotoxicity research. | |||||||||||||||||||||
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References
- [1]. Peck Y, et al. Multi-drug cocktails: Impurities in commonly used illicit drugs seized by police in Queensland, Australia. Drug and alcohol dependence. 2019 Aug 1;201:49-57.
- [2]. Zeng X, et al. A molecular pyroelectric enabling broadband photo-pyroelectric effect towards self-driven wide spectral photodetection. Nature communications. 2023 Sep 19;14(1):5821.
- [3]. Xu P, et al. N-isopropylbenzylamine, a methamphetamine mimics, produces toxicity via increasing nitric oxide in vitro. Toxicology. 2022 Oct;480:153337.
- [4]. Verma S, et al. Comparative Analysis of Benchtop NMR and HPLC-UV for Illicit Drug Mixtures. Magnetic resonance in chemistry : MRC. 2025 Nov;63(11):895-911.
