1838123-22-0
1838123-22-0
Chemical Structure
(R,R)-CXCR2-IN-2
- CAS No.: 1838123-22-0
- Formula:C18H23ClN2O5S
- Molecular Weight:414.90
IUPAC Name: 1-(4-chloro-2-hydroxy-3-(((R)-3-methyltetrahydrofuran-3-yl)sulfonyl)phenyl)-3-((R)-2-methylcyclopent-2-en-1-yl)urea
InChIKey: DNXKACKCTLURQN-FZKQIMNGSA-N
SMILES: O=S(C1=C(C(NC(N[C@H]2C(C)=CCC2)=O)=CC=C1Cl)O)([C@@]3(CCOC3)C)=O
Biological Activity: (R,R)-CXCR2-IN-2 (compound 67), diastereoisomer of CXCR2-IN-2 (compound 68) (HY-120878), is a CXCR2 antagonist with a pIC50 of 9 and 6.8 in the Tango assay and d in the HWB Gro-α induced CD11b expression assay, respectively[1].
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(R,R)-CXCR2-IN-2 | 98.79% | (R,R)-CXCR2-IN-2 (compound 67), diastereoisomer of CXCR2-IN-2 (compound 68) (HY-120878), is a CXCR2 antagonist with a pIC50 of 9 and 6.8 in the Tango assay and d in the HWB Gro-α induced CD11b expression assay, respectively. | ||||||||||||||||||||
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