1841460-82-9
1841460-82-9
Chemical Structure
TH1020
- CAS No.: 1841460-82-9
- Formula:C23H15N7S2
- Molecular Weight:453.54
IUPAC Name: 4-((4-benzyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)pyrido[3',2':4,5]thieno[3,2-d]pyrimidine
InChIKey: CBBXTGWSGPEJEE-UHFFFAOYSA-N
SMILES: C12=NC=NC(SC3=NN=C(N3CC4=CC=CC=C4)C5=CC=NC=C5)=C1SC6=NC=CC=C62
Biological Activity: TH1020 is a potent and selective toll-like receptor 5 (TLR5)/flagellin complex antagonist with an IC50 of 0.85 μM. TH1020 inhbits flagellin-induced TLR5 signaling. TH1020 is inactive against TLR2, TLR3, TLR4, TLR7 and TLR8[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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TH1020 | 99.81% | TH1020 is a potent and selective toll-like receptor 5 (TLR5)/flagellin complex antagonist with an IC50 of 0.85 μM. TH1020 inhbits flagellin-induced TLR5 signaling. TH1020 is inactive against TLR2, TLR3, TLR4, TLR7 and TLR8. | ||||||||||||||||||||
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