18463-11-1
Chemical Structure
Rhizocarpic acid
- CAS No.: 18463-11-1
- Formula:C28H23NO6
- Molecular Weight:469.49
IUPAC Name: methyl (Z)-(2-(3-hydroxy-5-oxo-4-phenylfuran-2(5H)-ylidene)-2-phenylacetyl)-L-phenylalaninate
InChIKey: DKDGWAKCXBFTMM-KFHWJWAOSA-N
SMILES: COC([C@H](CC1=CC=CC=C1)NC(/C(C2=CC=CC=C2)=C3C(O)=C(C4=CC=CC=C4)C(O/3)=O)=O)=O
Biological Activity: Rhizocarpic acid (Compound 2) is a secondary metabolite of lichen. Rhizocarpic acid effectively inhibits the growth of bacteria, such as Bacillus subtilis and Staphylococcus aureus, as well as murine myeloma NS-1 cells. Rhizocarpic acid is an antioxidant and an insect antifeedant with an ED50 of 71 μmol/g dry weight against neonate larvae of the Egyptian cotton leaf worm Spodoptera littoralis[1][2].
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Rhizocarpic acid | Rhizocarpic acid (Compound 2) is a secondary metabolite of lichen. Rhizocarpic acid effectively inhibits the growth of bacteria, such as Bacillus subtilis and Staphylococcus aureus, as well as murine myeloma NS-1 cells. Rhizocarpic acid is an antioxidant and an insect antifeedant with an ED50 of 71 μmol/g dry weight against neonate larvae of the Egyptian cotton leaf worm Spodoptera littoralis. | |||||||||||||||||||||
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References
- [1]. James PJC, et al. Synthesis, Characterization, and Bioactivity of the Lichen Pigments Pulvinamide, Rhizocarpic Acid, and Epanorin and Congeners. J Nat Prod. 2023 Mar 24;86(3):550-556. [Content Brief]
- [2]. Hidalgo ME, et al. Photophysical, photochemical, and thermodynamic properties of shikimic acid derivatives: calycin and rhizocarpic acid (lichens). J Photochem Photobiol B. 2002 Apr;66(3):213-7. [Content Brief]
