185039-99-0
185039-99-0
Chemical Structure
PD 173955 analog 1
- CAS No.: 185039-99-0
- Formula:C21H14Cl2N4O3
- Molecular Weight:441.27
IUPAC Name: 3-((6-(2,6-dichlorophenyl)-8-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)benzoic acid
InChIKey: RBURTLAMOSHNGX-UHFFFAOYSA-N
SMILES: O=C(O)C1=CC=CC(NC2=NC=C(C=C(C3=C(Cl)C=CC=C3Cl)C(N4C)=O)C4=N2)=C1
Biological Activity: PD 173955 analog 1 (Compound 26) is an analog of PD 173955 (HY-10395). PD 173955 analog 1 is an inhibitor for EGFR kinase, which exhibits antitumor and toxicological properties. PD 173955 analog 1 exhibits an in silico IC50 of 0.19 μM[1].
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PD 173955 analog 1 | PD 173955 analog 1 (Compound 26) is an analog of PD 173955 (HY-10395). PD 173955 analog 1 is an inhibitor for EGFR kinase, which exhibits antitumor and toxicological properties. PD 173955 analog 1 exhibits an in silico IC50 of 0.19 μM. | |||||||||||||||||||||
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