185435-28-3
Chemical Structure
1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphatidylglycerol
Synonym(s): POPG
- CAS No.: 185435-28-3
- Formula:C40H77O10P
- Molecular Weight:749.01
IUPAC Name: methyl-d3 decanoate
InChIKey: PAZGBAOHGQRCBP-DDDNOICHSA-N
SMILES: OCC(O)COP(OC[C@H](OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O)(O)=O
Biological Activity: 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphatidylglycerol (POPG) is an anionic phosphatidylglycerol that often serves as a key component to co-construct model phospholipid bilayers with phosphatidylcholine (e.g., at a 3:1 POPC:POPG ratio) for investigating the structure and dynamics of transmembrane proteins. 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphatidylglycerol acts as a fundamental material for mimicking the physicochemical properties of biological membranes and enables the elucidation of membrane protein interaction mechanisms[1][2].
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1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphatidylglycerol | 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphatidylglycerol (POPG) is an anionic phosphatidylglycerol that often serves as a key component to co-construct model phospholipid bilayers with phosphatidylcholine (e.g., at a 3:1 POPC:POPG ratio) for investigating the structure and dynamics of transmembrane proteins. 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphatidylglycerol acts as a fundamental material for mimicking the physicochemical properties of biological membranes and enables the elucidation of membrane protein interaction mechanisms. | |||||||||||||||||||||
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References
- [1]. Marti J, Calero C. Modeling and simulation of lipid membranes[J]. Membranes, 2022, 12(6): 549.
- [2]. Karathanou K, et al. Dynamic Water Hydrogen-Bond Networks at the Interface of a Lipid Membrane Containing Palmitoyl-Oleoyl Phosphatidylglycerol. J Membr Biol. 2018;251(3):461-473. [Content Brief]
