185461-45-4
185461-45-4
Chemical Structure
(Sar1,Ile4,8)-Angiotensin II
- CAS No.: 185461-45-4
- Formula:C43H75N13O9
- Molecular Weight:918.14
InChIKey: IOOIRDJKADTVNI-MMYICMJWSA-N
SMILES: CNCC(N[C@@H](CCCNC(N)=N)C(N[C@@H](C(C)C)C(N[C@@H]([C@@H](C)CC)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC1=CN=CN1)C(N2[C@@H](CCC2)C(N[C@H](C(O)=O)[C@@H](C)CC)=O)=O)=O)=O)=O)=O)=O
Biological Activity: (Sar1,Ile4,8)-Angiotensin II is a functionally selective angiotensin II type 1 receptor (AT1R) agonist. (Sar1,Ile4,8)-Angiotensin II potentiates insulin-stimulated insulin receptor (IR) signaling and glycogen synthesis. (Sar1,Ile4,8)-Angiotensin II potentiates insulin-stimulated phosphorylation of Akt and GSK3α/β[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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(Sar1,Ile4,8)-Angiotensin II | 98.88% | (Sar1,Ile4,8)-Angiotensin II is a functionally selective angiotensin II type 1 receptor (AT1R) agonist. (Sar1,Ile4,8)-Angiotensin II potentiates insulin-stimulated insulin receptor (IR) signaling and glycogen synthesis. (Sar1,Ile4,8)-Angiotensin II potentiates insulin-stimulated phosphorylation of Akt and GSK3α/β. | ||||||||||||||||||||
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