185954-27-2

Tofimilast Chemical Structure
185954-27-2

Chemical Structure

Tofimilast

  • CAS No.: 185954-27-2
  • Formula:C18H21N5S
  • Molecular Weight:339.46

IUPAC Name: 9-cyclopentyl-7-ethyl-3-(thiophen-2-yl)-6,9-dihydro-5H-pyrazolo[3,4-c][1,2,4]triazolo[4,3-a]pyridine

InChIKey: DHCOPPHTVOXDKU-UHFFFAOYSA-N

SMILES: CCC1=NN(C2=C1CCN3C2=NN=C3C4=CC=CS4)C5CCCC5

Biological Activity: Tofimilast is an inhibitor of Phosphodiesterase 4 (PDE4) with an IC50 of 0.14 μM. Tofimilast exerts its anti-inflammatory effects by inhibiting the activity of PDE4, thereby increasing intracellular levels of cAMP[1].

Cat. No. Product Name Purity Description Pricing
HY-106137
Tofimilast 99.55% Tofimilast is an inhibitor of Phosphodiesterase 4 (PDE4) with an IC50 of 0.14 μM. Tofimilast exerts its anti-inflammatory effects by inhibiting the activity of PDE4, thereby increasing intracellular levels of cAMP.
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This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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References