187724-85-2

L-741671 Chemical Structure
187724-85-2

Chemical Structure

L-741671

  • CAS No.: 187724-85-2
  • Formula:C23H22F6N4O2
  • Molecular Weight:500.44

IUPAC Name: 5-(((2R,3R)-3-((3,5-bis(trifluoromethyl)benzyl)oxy)-2-phenylpiperidin-1-yl)methyl)-1,2-dihydro-3H-1,2,4-triazol-3-one

InChIKey: ZUWHBRRBKKTMQO-UYAOXDASSA-N

SMILES: O=C1NNC(CN2[C@@H]([C@@H](CCC2)OCC3=CC(C(F)(F)F)=CC(C(F)(F)F)=C3)C4=CC=CC=C4)=N1

Biological Activity: L-741671 is a selective and brain-permeable antagonist of neurokininl (hNKI) receptor, with Kis of 64 nM, 0.03 nM and 0.7 nM in rat, human and ferret, respectively[1].

Cat. No. Product Name Purity Description Pricing
HY-119095 		L-741671 L-741671 is a selective and brain-permeable antagonist of neurokininl (hNKI) receptor, with Kis of 64 nM, 0.03 nM and 0.7 nM in rat, human and ferret, respectively.
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This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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References

Keywords