18828-58-5
Chemical Structure
Propionyl-DL-carnitine chloride
- CAS No.: 18828-58-5
- Formula:C10H20ClNO4
- Molecular Weight:253.72
IUPAC Name: 3-carboxy-N,N,N-trimethyl-2-(propionyloxy)propan-1-aminium chloride
InChIKey: KTFMPDDJYRFWQE-UHFFFAOYSA-N
SMILES: CCC(OC(CC(O)=O)C[N+](C)(C)C)=O.[Cl-]
Biological Activity: Propionyl-DL-carnitine chloride is a carnitine derivative. Propionyl-DL-carnitine chloride can be used for the research of inflammation[1][2][3][4].
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Propionyl-DL-carnitine chloride | 98.10% | Propionyl-DL-carnitine chloride is a carnitine derivative. Propionyl-DL-carnitine chloride can be used for the research of inflammation. | ||||||||||||||||||||
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Propionyl-DL-carnitine chloride (Standard) | ≥98% | Propionyl-DL-carnitine (chloride) (Standard) is the analytical standard of Propionyl-DL-carnitine (chloride). This product is intended for research and analytical applications. Propionyl-DL-carnitine chloride is a carnitine derivative. Propionyl-DL-carnitine chloride can be used for the research of inflammation. | ||||||||||||||||||||
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(±)-Hexanoylcarnitine chloride | 98.0% | (±)-Hexanoylcarnitine chloride is a fatty acid metabolite that breaks down fatty acids into energy that can be used by the body. (±)-Hexanoylcarnitine chloride also serves as a specific and easily detectable biomarker for rat skeletal muscle toxicity. Cerivastatin (HY-129458) and TMPD (HY-W012145) induce an increase in Hexanoylcarnitine in rats in a metabolomic analysis of the rectus femoris muscle. In type 2 diabetes, Hexanoylcarnitine is also significantly associated with and improves prediction of all-cause mortality. Hexanoylcarnitine is a biomarker for the identification of novel pathogenic pathways. | ||||||||||||||||||||
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Isobutyryl-L-carnitine chloride (Standard) | ≥98% | Isobutyryl-L-carnitine chloride (Standard) is the analytical standard of Isobutyryl-L-carnitine chloride (HY-113165A). This product is intended for research and analytical applications. Isobutyryl-L-carnitine chloride is a biomarker. Isobutyryl-L-carnitine chloride is a product of acyl-CoA dehydrogenases involved in fatty acid β-oxidation, and it buffers the mitochondrial acyl-CoA/CoA ratio, oxidizes branched-chain amino acids, and supports the endogenous antioxidant defense system. Isobutyryl-L-carnitine chloride is a plasma biomarker of hepatic OCT1 transporter inhibition. Isobutyryl-L-carnitine chloride is a urinary biomarker of renal cell carcinoma, and its levels are elevated one year after nephrectomy compared with before nephrectomy. Isobutyryl-L-carnitine chloride can be used in research on renal cell carcinoma. | ||||||||||||||||||||
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Butyryl-L-carnitine chloride | 99.55% | Butyryl-L-carnitine chloride is an acylcarnitine that can be isolated from Plasma/Serum. | ||||||||||||||||||||
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Hexanoyl-L-carnitine chloride | 99.61% | Hexanoyl-L-carnitine (chloride) is an ester product. | ||||||||||||||||||||
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Heptanoyl-L-carnitine chloride | Heptanoyl-L-carnitine chloride (trans-3,4-methylene-heptanoylcarnitine) is an acylcarnitine. Heptanoyl-L-carnitine chloride causes exercise-induced alterations in the human metabolome in plasma and skeletal muscle tissue. | |||||||||||||||||||||
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Valeryl-L-carnitine chloride | Valeryl-L-carnitine (chloride) is an ester product. | |||||||||||||||||||||
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Isovalerylcarnitine chloride | 99.48% | Isovalerylcarnitine chloride is a metabolite of leucine. Isovalerylcarnitine chloride can specifically activate calpain in human neutrophils. Isovalerylcarnitine chloride inhibits tumor cell proliferation and induces apoptosis. Elevated circulating levels of Isovalerylcarnitine chloride are negatively correlated with reduced lung cancer risk. | ||||||||||||||||||||
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Malonyl-L-Carnitine chloride | Malonyl-L-Carnitine (chloride) is an ester product. | |||||||||||||||||||||
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Levocarnitine propionate hydrochloride (Standard) | ≥98% | Levocarnitine propionate hydrochloride (Standard) is the analytical standard of Adrenalone (hydrochloride). This product is intended for research and analytical applications. Levocarnitine propionate hydrochloride (L-Propionylcarnitine chloride; ST-261) is a ligand of carnitine acetyltransferase (CAT) with high enzyme affinity. Levocarnitine propionate hydrochloride possesses antioxidant activity. Levocarnitine propionate hydrochloride increases intracellular L-carnitine reserves. Levocarnitine propionate hydrochloride exerts a protective effect against myocardial ischemia-reperfusion injury. Levocarnitine propionate hydrochloride can be used in research related to myocardial ischemia-reperfusion injury and chronic ischemic heart disease. | ||||||||||||||||||||
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Levocarnitine propionate-d3 hydrochloride | 98.0% | Levocarnitine propionate-d3 (hydrochloride) is the deuterium labeled Levocarnitine propionate hydrochloride. Levocarnitine propionate hydrochloride (L-Propionylcarnitine chloride; ST-261) is a ligand of carnitine acetyltransferase (CAT) with high enzyme affinity. Levocarnitine propionate hydrochloride possesses antioxidant activity. Levocarnitine propionate hydrochloride increases intracellular L-carnitine reserves. Levocarnitine propionate hydrochloride exerts a protective effect against myocardial ischemia-reperfusion injury. Levocarnitine propionate hydrochloride can be used in research related to myocardial ischemia-reperfusion injury and chronic ischemic heart disease. | ||||||||||||||||||||
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References
- [1]. Palmieri L, et al. Protection of beta-thalassaemic erythrocytes from oxidative stress by propionyl carnitine. Int J Tissue React. 1994;16(3):121-9. [Content Brief]
- [2]. Tassani V, et al. Anaplerotic effect of propionyl carnitine in rat heart mitochondria. Biochem Biophys Res Commun. 1994 Mar 15;199(2):949-53. [Content Brief]
- [3]. Morand R, et al. Effect of carnitine, acetyl-, and propionylcarnitine supplementation on the body carnitine pool, skeletal muscle composition, and physical performance in mice. Eur J Nutr. 2014 Sep;53(6):1313-25. [Content Brief]
- [4]. Bertelli A, et al. Effect of propionyl carnitine on energy charge and adenine nucleotide content of cardiac endothelial cells during hypoxia. Int J Tissue React. 1991;13(1):37-40. [Content Brief]