1883329-51-8
1883329-51-8
Chemical Structure
Foliglurax
Synonym(s): PXT002331
- CAS No.: 1883329-51-8
- Formula:C23H23N3O3S
- Molecular Weight:421.51
IUPAC Name: (E)-6-(3-morpholinopropyl)-2-(thieno[3,2-c]pyridin-6-yl)-4H-chromen-4-one oxime
InChIKey: ZTEDNASHAWNBKQ-NCELDCMTSA-N
SMILES: O/N=C1C=C(C2=CC3=C(C=CS3)C=N2)OC4=CC=C(CCCN5CCOCC5)C=C\14
Biological Activity: Foliglurax (PXT002331) is a highly selective and potent, brain-penetrant metabotropic glutamate receptor 4 positive allosteric modulator (mGluR4 PAM) with an EC50 of 79 nM[1]. Antiparkinsonian effect[1].
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Foliglurax | Foliglurax (PXT002331) is a highly selective and potent, brain-penetrant metabotropic glutamate receptor 4 positive allosteric modulator (mGluR4 PAM) with an EC50 of 79 nM. Antiparkinsonian effect. | |||||||||||||||||||||
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