1883518-31-7
1883518-31-7
Chemical Structure
GNE-0723
- CAS No.: 1883518-31-7
- Formula:C16H8ClF6N5OS
- Molecular Weight:467.78
IUPAC Name: (1R,2R)-2-(7-((5-chloro-3-(trifluoromethyl)-1H-pyrazol-1-yl)methyl)-5-oxo-2-(trifluoromethyl)-5H-thiazolo[3,2-a]pyrimidin-3-yl)cyclopropane-1-carbonitrile
InChIKey: FTIBNGABJNFFAI-POYBYMJQSA-N
SMILES: N#C[C@H]1[C@H](C2=C(C(F)(F)F)SC3=NC(CN4N=C(C(F)(F)F)C=C4Cl)=CC(N32)=O)C1
Biological Activity: GNE-0723 is a brain permeable positive allosteric modulator of NMDAR, with an EC50 of 21 nM for GluN2A, 7.4 and 6.2 μM for GluN2C and GluN2D, respectively[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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GNE-0723 | 99.93% | GNE-0723 is a brain permeable positive allosteric modulator of NMDAR, with an EC50 of 21 nM for GluN2A, 7.4 and 6.2 μM for GluN2C and GluN2D, respectively. | ||||||||||||||||||||
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