18887-18-8
18887-18-8
Chemical Structure
Hydroxytanshinone IIA
- CAS No.: 18887-18-8
- Formula:C19H18O4
- Molecular Weight:310.34
IUPAC Name: 9-hydroxy-1,6,6-trimethyl-6,7,8,9-tetrahydrophenanthro[1,2-b]furan-10,11-dione
InChIKey: UPCWCCRFMPIOAP-UHFFFAOYSA-N
SMILES: O=C(C1=C2C=CC3=C1C(O)CCC3(C)C)C(C4=C2OC=C4C)=O
Biological Activity: Hydroxytanshinone IIA is a hydrolytic metabolite of Tanshinone IIA (HY-N0135). Tanshinone IIA inhibits angiogenesis by targeting the protein kinase domain of VEGF/VEGFR2. Hydroxytanshinone IIA exhibits antioxidant and anti-inflammatory activities. Hydroxytanshinone IIA can be used in studies of angina pectoris and myocardial infarction[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Hydroxytanshinone IIA | 99.83% | Hydroxytanshinone IIA is a hydrolytic metabolite of Tanshinone IIA (HY-N0135). Tanshinone IIA inhibits angiogenesis by targeting the protein kinase domain of VEGF/VEGFR2. Hydroxytanshinone IIA exhibits antioxidant and anti-inflammatory activities. Hydroxytanshinone IIA can be used in studies of angina pectoris and myocardial infarction. | ||||||||||||||||||||
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References
- [1]. Li P, et al. Simultaneous determination of tanshinone IIA and its three hydroxylated metabolites by liquid chromatography/tandem mass spectrometry. Rapid communications in mass spectrometry : RCM. 2006;20(5):815-22. [Content Brief]
- [2]. Li P, et al. Characterization of metabolites of tanshinone IIA in rats by liquid chromatography/tandem mass spectrometry. Journal of mass spectrometry : JMS. 2006 May;41(5):670-84.
- [3]. Li P, et al. Identification of tanshinone IIA metabolites in rat liver microsomes by liquid chromatography-tandem mass spectrometry. Journal of chromatography. A. 2006 Feb 03;1104(1-2):366-9.
