189064-08-2
![[Ala92]-p16 (84-103) Chemical Structure](http://file.medchemexpress.cn/product_pic/hy-p1109.gif "[Ala92]-p16 (84-103) Chemical Structure")
189064-08-2
Chemical Structure
[Ala92]-p16 (84-103)
- CAS No.: 189064-08-2
- Formula:C93H155N31O26
- Molecular Weight:2123.42
InChIKey: SRSWQMWUNOIPDH-QCDQIEFZSA-N
SMILES: [Asp-Ala-Ala-Arg-Glu-Gly-Phe-Leu-Ala-Thr-Leu-Val-Val-Leu-His-Arg-Ala-Gly-Ala-Arg]
Biological Activity: [Ala92]-p16 (84-103) is a peptide derived from the p16CDKN2/INK4a (p16) tumor suppressor protein. [Ala92]-p16 (84-103) binds to both cdk4 and cdk6 and inhibits cdk4-cyclin D1 kinase activity in vitro (IC50: 1.5 μM). [Ala92]-p16 (84-103) blocks cell cycle progression through the G1 phase[1].
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[Ala92]-p16 (84-103) | 98.16% | [Ala92]-p16 (84-103) is a peptide derived from the p16CDKN2/INK4a (p16) tumor suppressor protein. [Ala92]-p16 (84-103) binds to both cdk4 and cdk6 and inhibits cdk4-cyclin D1 kinase activity in vitro (IC50: 1.5 μM). [Ala92]-p16 (84-103) blocks cell cycle progression through the G1 phase. | ||||||||||||||||||||
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