1899061-36-9
1899061-36-9
Chemical Structure
(14S,15R)-14-Deoxyoxacyclododecindione
- CAS No.: 1899061-36-9
- Formula:C18H21ClO5
- Molecular Weight:352.81
InChIKey: SQFBFKKGAWCQAU-XHHWIUDKSA-N
SMILES: OC1=C(C(/C(C)=C/CC[C@H](C)[C@@H](C)OC2=O)=O)C(C2)=C(Cl)C(O)=C1
Biological Activity:
(14S,15R)-14-Deoxyoxacyclododecindione (Compound 3) acts as an inhibitor of TGF-β-dependent Smad2/3 and IL-4-dependent STAT6, with IC50 values of 90 nM and 20 nM, respectively. (14S,15R)-14-deoxyoxacyclododecindione is a potent IL-4 inhibitor with an IC50
value of 20 nM. (14S,15R)-14-Deoxyoxacyclododecindione is applicable to the research of chronic inflammation and fibrotic diseases[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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(14S,15R)-14-Deoxyoxacyclododecindione | (14S,15R)-14-Deoxyoxacyclododecindione (Compound 3) acts as an inhibitor of TGF-β-dependent Smad2/3 and IL-4-dependent STAT6, with IC50 values of 90 nM and 20 nM, respectively. (14S,15R)-14-deoxyoxacyclododecindione is a potent IL-4 inhibitor with an IC50 value of 20 nM. (14S,15R)-14-Deoxyoxacyclododecindione is applicable to the research of chronic inflammation and fibrotic diseases. |
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