1902146-75-1
1902146-75-1
Chemical Structure
RI(dl)-2
- CAS No.: 1902146-75-1
- Formula:C19H17N3
- Molecular Weight:287.36
IUPAC Name: N-ethyl-4-(pyrrolo[1,2-a]quinoxalin-4-yl)aniline
InChIKey: OEUMSXQHYXCNBG-UHFFFAOYSA-N
SMILES: CCNC(C=C1)=CC=C1C2=NC3=C(N4C=CC=C42)C=CC=C3
Biological Activity: RI(dl)-2 blocks RAD51’s D-loop activity in biochemical systems with an IC50 value of 11.1 µM and inhibits homologous recombination (HR) activity with an IC50 value of 3.0 µM. RI(dl)-2 inhibits HR-mediated repair of DNA double strand breaks and sensitizes different cancer cell lines[1].
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RI(dl)-2 | RI(dl)-2 blocks RAD51’s D-loop activity in biochemical systems with an IC50 value of 11.1 µM and inhibits homologous recombination (HR) activity with an IC50 value of 3.0 µM. RI(dl)-2 inhibits HR-mediated repair of DNA double strand breaks and sensitizes different cancer cell lines. | |||||||||||||||||||||
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