19046-60-7
Chemical Structure
Galactose 1-phosphate Potassium salt
- CAS No.: 19046-60-7
- Formula:C6H11K2O9P
- Molecular Weight:336.32
IUPAC Name: potassium (2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl phosphate
InChIKey: KCIDZIIHRGYJAE-YGFYJFDDSA-L
SMILES: O=P(O[K])(O[K])O[C@H]1O[C@@H]([C@H](O)[C@H](O)[C@H]1O)CO
Biological Activity: Galactose 1-phosphate Potassium salt acts as a competitive substrate inhibitor of galactose-1-phosphate uridylyltransferase (GALT). Galactose 1-phosphate Potassium salt is a competitive inhibitor of Phosphoglucomutase, yet the rate at which this enzyme converts Galactose 1-phosphate to Galactose-6-phosphate is 400 times slower than the rate of converting Glucose-1-phosphate. Galactose 1-phosphate Potassium salt can be used in studies related to Saccharomyces cerevisiae infection and type I galactosemia[1][2].
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Galactose 1-phosphate Potassium salt | 99.0% | Galactose 1-phosphate Potassium salt acts as a competitive substrate inhibitor of galactose-1-phosphate uridylyltransferase (GALT). Galactose 1-phosphate Potassium salt is a competitive inhibitor of Phosphoglucomutase, yet the rate at which this enzyme converts Galactose 1-phosphate to Galactose-6-phosphate is 400 times slower than the rate of converting Glucose-1-phosphate. Galactose 1-phosphate Potassium salt can be used in studies related to Saccharomyces cerevisiae infection and type I galactosemia. | ||||||||||||||||||||
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Galactose 1-phosphate-13C6 potassium | 99.91% | Galactose 1-phosphate-13C6 potassium is the 13C-labeled Galactose 1-phosphate Potassium salt (HY-113143A). Galactose 1-phosphate Potassium salt is is an intermediate in the galactose metabolism and nucleotide sugars. | ||||||||||||||||||||
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Galactose 1-phosphate-13C-1 potassium | 99.16% | Galactose 1-phosphate-13C-1 potassium is the 13C-labeled Galactose 1-phosphate Potassium salt (HY-113143A). Galactose 1-phosphate Potassium salt acts as a competitive substrate inhibitor of galactose-1-phosphate uridylyltransferase (GALT). Galactose 1-phosphate Potassium salt is a competitive inhibitor of Phosphoglucomutase, yet the rate at which this enzyme converts Galactose 1-phosphate to Galactose-6-phosphate is 400 times slower than the rate of converting Glucose-1-phosphate. Galactose 1-phosphate Potassium salt can be used in studies related to Saccharomyces cerevisiae infection and type I galactosemia. | ||||||||||||||||||||
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Galactose 1-phosphate-13C potassium | 98.8% | Galactose 1-phosphate-13C potassium is the 13C-labeled Galactose 1-phosphate Potassium salt (HY-113143A). Galactose 1-phosphate Potassium salt acts as a competitive substrate inhibitor of galactose-1-phosphate uridylyltransferase (GALT). Galactose 1-phosphate Potassium salt is a competitive inhibitor of Phosphoglucomutase, yet the rate at which this enzyme converts Galactose 1-phosphate to Galactose-6-phosphate is 400 times slower than the rate of converting Glucose-1-phosphate. Galactose 1-phosphate Potassium salt can be used in studies related to Saccharomyces cerevisiae infection and type I galactosemia. | ||||||||||||||||||||
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References
- [1]. metabolism pathwaysMcCorvie TJ, et al. The structural and molecular biology of type I galactosemia: Enzymology of galactose 1-phosphate uridylyltransferase. IUBMB Life. 2011 Sep;63(9):694-700. [Content Brief]
- [2]. Machado, C. M., et al., (2017). The galactose-induced decrease in phosphate levels leads to toxicity in yeast models of galactosemia. Biochimica et biophysica acta. Molecular basis of disease, 1863(6), 1403–1409. [Content Brief]
