1911631-77-0
1911631-77-0
Chemical Structure
Antitumor agent-214
- CAS No.: 1911631-77-0
- Formula:C19H16N2O4
- Molecular Weight:336.34
InChIKey: XFVTYRJIEPULDC-CSKARUKUSA-N
SMILES: O=C1NC(/C=C/C(C2=CC(OC)=CC=C2OC)=O)=NC3=C1C=CC=C3
Biological Activity: Antitumor agent-214 is a chalcone analogue with anti-tumor activity. Antitumor agent-214 induces cell cycle arrest and apoptosis in tumor cells, disrupts mitochondrial metabolism, and upregulates the expression of caspase 3, caspase 7 and caspase 9, downregulates PARP1. Antitumor agent-214 can be used for anti-tumor research related to colorectal cancer, breast cancer, lung cancer, and cervical cancer[1].
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Antitumor agent-214 | Antitumor agent-214 is a chalcone analogue with anti-tumor activity. Antitumor agent-214 induces cell cycle arrest and apoptosis in tumor cells, disrupts mitochondrial metabolism, and upregulates the expression of caspase 3, caspase 7 and caspase 9, downregulates PARP1. Antitumor agent-214 can be used for anti-tumor research related to colorectal cancer, breast cancer, lung cancer, and cervical cancer. | |||||||||||||||||||||
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