192231-16-6
192231-16-6
Chemical Structure
Altinicline maleate
Synonym(s): SIB-1508Y
- CAS No.: 192231-16-6
- Formula:C16H18N2O4
- Molecular Weight:302.33
IUPAC Name: (S)-3-ethynyl-5-(1-methylpyrrolidin-2-yl)pyridine maleate
InChIKey: BCPPKHPWLRPWBJ-OURKGEEVSA-N
SMILES: CN1[C@H](C2=CN=CC(C#C)=C2)CCC1.OC(/C=C\C(O)=O)=O
Biological Activity: Altinicline maleate (SIB-1508Y) is a selective α4β2 nicotinic acetylcholine receptor (nAChR) agonist, with no activity against α7 or α1β1γδ nAChRs and only extremely low activity against α3β4 nAChRs. Altinicline maleate reverses escape deficits and increases avoidance responses. Altinicline maleate is applicable to research related to depression[1].
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Altinicline maleate | Altinicline maleate (SIB-1508Y) is a selective α4β2 nicotinic acetylcholine receptor (nAChR) agonist, with no activity against α7 or α1β1γδ nAChRs and only extremely low activity against α3β4 nAChRs. Altinicline maleate reverses escape deficits and increases avoidance responses. Altinicline maleate is applicable to research related to depression. | |||||||||||||||||||||
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