1926163-52-1
1926163-52-1
Chemical Structure
Met-Gly-Pro-AMC
- CAS No.: 1926163-52-1
- Formula:C22H28N4O5S
- Molecular Weight:460.55
InChIKey: SBIKNEVHKGLANK-IRXDYDNUSA-N
SMILES: CC(C1=CC=C(NC([C@H]2N(CCC2)C(CNC([C@@H](N)CCSC)=O)=O)=O)C=C1O3)=CC3=O
Biological Activity: Met-Gly-Pro-AMC is a fluorescent peptide substrate active against *Caenorhabditis elegans* DPF-3, hDPP4, and methionyl aminopeptidase 2 (MetAP2). Met-Gly-Pro-AMC undergoes cleavage via tripeptidyl peptidase activity to release a fluorescent product. Met-Gly-Pro-AMC is used to detect the activities of tripeptidyl peptidases and MetAP2 peptidases in in vitro enzyme activity assays[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Met-Gly-Pro-AMC | 99.74% | Met-Gly-Pro-AMC is a fluorescent peptide substrate active against *Caenorhabditis elegans* DPF-3, hDPP4, and methionyl aminopeptidase 2 (MetAP2). Met-Gly-Pro-AMC undergoes cleavage via tripeptidyl peptidase activity to release a fluorescent product. Met-Gly-Pro-AMC is used to detect the activities of tripeptidyl peptidases and MetAP2 peptidases in in vitro enzyme activity assays. | ||||||||||||||||||||
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References
- [1]. Trivedi A, et al. The Caenorhabditis elegans DPF-3 and human DPP4 have tripeptidyl peptidase activity. FEBS letters. 2026 Feb;600(3):324-333. [Content Brief]
- [2]. Ng JY, et al. Tyrosine nitration moderates the peptidase activity of human methionyl aminopeptidase 2. Biochemical and biophysical research communications. 2013 Oct 11;440(1):37-42. [Content Brief]
