193022-04-7
193022-04-7
Chemical Structure
CTS-1027
Synonym(s): Ro 1130830; RS 130830
- CAS No.: 193022-04-7
- Formula:C19H20ClNO6S
- Molecular Weight:425.88
IUPAC Name: 4-(((4-(4-chlorophenoxy)phenyl)sulfonyl)methyl)-N-hydroxytetrahydro-2H-pyran-4-carboxamide
InChIKey: ROSNVSQTEGHUKU-UHFFFAOYSA-N
SMILES: O=C(NO)C1(CCOCC1)CS(=O)(C2=CC=C(C=C2)OC3=CC=C(C=C3)Cl)=O
Biological Activity: CTS-1027 is a potent small molecule inhibitor of MMPs, with IC50s of 0.3 nM, 0.5 nM for MMP2, MMP13, respectively, and has > 1,000 fold selectivity over MMP1.
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CTS-1027 | 99.24% | CTS-1027 is a potent small molecule inhibitor of MMPs, with IC50s of 0.3 nM, 0.5 nM for MMP2, MMP13, respectively, and has > 1,000 fold selectivity over MMP1. | ||||||||||||||||||||
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CTS-1027 (Standard) | ≥98% | CTS-1027 (Standard) is the analytical standard of CTS-1027 (HY-10398). This product is intended for research and analytical applications. CTS-1027 is a potent small molecule inhibitor of MMPs, with IC50s of 0.3 nM, 0.5 nM for MMP2, MMP13, respectively, and has > 1,000 fold selectivity over MMP1. | ||||||||||||||||||||
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