193613-75-1
193613-75-1
Chemical Structure
Osteoblast-Adhesive Peptide
- CAS No.: 193613-75-1
- Formula:C21H43N11O6
- Molecular Weight:545.64
InChIKey: PXOPRMBOLQDHOB-AJNGGQMLSA-N
SMILES: N=C(N)NCCC[C@@H](C(O)=O)NC([C@H](CO)NC([C@H](CCCNC(N)=N)NC([C@@H](N)CCCCN)=O)=O)=O
Biological Activity: Osteoblast-Adhesive Peptide (Lys-Arg-Ser-Arg) is an adhesion peptide that can be used as a dental/orthopedic biomaterial to support and enhance osteoblast (anchorage-dependent cell) adhesion. Osteoblasts adhere via both integrin-mediated and proteoglycan-mediated mechanisms. Osteoblast-Adhesive Peptide may be osteoblast- or osteocyte-specific and participate in proteoglycan-mediated osteoblast adhesion[1][2].
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Osteoblast-Adhesive Peptide | Osteoblast-Adhesive Peptide (Lys-Arg-Ser-Arg) is an adhesion peptide that can be used as a dental/orthopedic biomaterial to support and enhance osteoblast (anchorage-dependent cell) adhesion. Osteoblasts adhere via both integrin-mediated and proteoglycan-mediated mechanisms. Osteoblast-Adhesive Peptide may be osteoblast- or osteocyte-specific and participate in proteoglycan-mediated osteoblast adhesion. | |||||||||||||||||||||
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References
- [1]. Dee KC, et al. Design and function of novel osteoblast-adhesive peptides for chemical modification of biomaterials. J Biomed Mater Res. 1998 Jun 5;40(3):371-7. [Content Brief]
- [2]. Dettin M, et al. Novel osteoblast-adhesive peptides for dental/orthopedic biomaterials. J Biomed Mater Res. 2002 Jun 5;60(3):466-71. [Content Brief]
