1936529-65-5
1936529-65-5
Chemical Structure
YKL-05-099
- CAS No.: 1936529-65-5
- Formula:C32H34ClN7O3
- Molecular Weight:600.11
IUPAC Name: 3-(2-chloro-6-methylphenyl)-7-((2-methoxy-4-(1-methylpiperidin-4-yl)phenyl)amino)-1-(5-methoxypyridin-2-yl)-3,4-dihydropyrimido[4,5-d]pyrimidin-2(1H)-one
InChIKey: VQINULODWGEVBB-UHFFFAOYSA-N
SMILES: O=C1N(C2=NC=C(OC)C=C2)C3=NC(NC4=CC=C(C5CCN(C)CC5)C=C4OC)=NC=C3CN1C6=C(C)C=CC=C6Cl
Biological Activity: YKL-05-099 is a salt-inducible kinase (SIK) inhibitor. YKL-05-099 binds to SIK1 and SIK3 with IC50s of ~10 and ~30 nM, respectively. YKL-05-099 has slightly less potent SIK2-inhibitory (IC50=40 nM)[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
YKL-05-099 | 99.73% | YKL-05-099 is a salt-inducible kinase (SIK) inhibitor. YKL-05-099 binds to SIK1 and SIK3 with IC50s of ~10 and ~30 nM, respectively. YKL-05-099 has slightly less potent SIK2-inhibitory (IC50=40 nM). | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
YKL-05-099 (Standard) | ≥98% | YKL-05-099 (Standard) is the analytical standard of YKL-05-099 (HY-101147). This product is intended for research and analytical applications. YKL-05-099 is a salt-inducible kinase (SIK) inhibitor. YKL-05-099 binds to SIK1 and SIK3 with IC50s of ~10 and ~30 nM, respectively. YKL-05-099 has slightly less potent SIK2-inhibitory (IC50=40 nM). | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
