194357-64-7
Chemical Structure
NSP-DMAE-NHS
- CAS No.: 194357-64-7
- Formula:C30H26N2O9S
- Molecular Weight:590.60
IUPAC Name: 3-(9-((4-(((2,5-dioxopyrrolidin-1-yl)oxy)carbonyl)-2,6-dimethylphenoxy)carbonyl)acridin-10-ium-10-yl)propane-1-sulfonate
InChIKey: AAYSIOJYGRABGS-UHFFFAOYSA-N
SMILES: O=C(C1=CC(C)=C(OC(C2=C3C=CC=CC3=[N+](CCCS(=O)([O-])=O)C4=C2C=CC=C4)=O)C(C)=C1)ON5C(CCC5=O)=O
Biological Activity: NSP-DMAE-NHS is an acridinium ester-based signal amplifier that can act as a luminescent probe to effectively improve the detection performance of biosensors. NSP-DMAE-NHS preserves the biochemical activity of biomolecules during the conjugation process. NSP-DMAE-NHS has been successfully applied to label mouse anti-human PI3 monoclonal antibodies for chemiluminescent immunoassays, as well as for pre-competitive chemiluminescent immunochromatographic detection of TP53 fusion proteins. NSP-DMAE-NHS can be used in detection studies of cancer and related biomarkers[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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NSP-DMAE-NHS | 99.48% | NSP-DMAE-NHS is an acridinium ester-based signal amplifier that can act as a luminescent probe to effectively improve the detection performance of biosensors. NSP-DMAE-NHS preserves the biochemical activity of biomolecules during the conjugation process. NSP-DMAE-NHS has been successfully applied to label mouse anti-human PI3 monoclonal antibodies for chemiluminescent immunoassays, as well as for pre-competitive chemiluminescent immunochromatographic detection of TP53 fusion proteins. NSP-DMAE-NHS can be used in detection studies of cancer and related biomarkers. | ||||||||||||||||||||
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References
- [1]. Wang L, et al. Development of a Competitive Chemiluminescent Assay for Quantitative Determination of TP53 Fusion Protein Using Reagent Strips. Appl Biochem Biotechnol. 2024;196(9):6315-6329. [Content Brief]
- [2]. Xu M, et al. Systematic analysis of serum peptidase inhibitor 3 in psoriasis diagnosis and treatment. Clin Rheumatol. 2024;43(11):3361-3372. [Content Brief]
