1947405-90-4
Chemical Structure
15-Deoxy-Δ12,14-Prostaglandin J2-2-glyceryl ester
- CAS No.: 1947405-90-4
- Formula:C23H34O5
- Molecular Weight:390.51
InChIKey: JGKIBUMNHSZUSL-SLDNAQRASA-N
SMILES: CCCCC/C=C/C=C1[C@H](C=CC\1=O)C/C=C\CCCC(OC(CO)CO)=O
Biological Activity: 15-Deoxy-Δ12,14-Prostaglandin J2-2-glyceryl ester is a derivate of 15-Deoxy-Δ-12,14-prostaglandin J2 (HY-108568). 15-Deoxy-Δ-12,14-prostaglandin J2 (15d-PGJ2) is a cyclopentenone prostaglandin and a metabolite of PGD2. 15-Deoxy-Δ-12,14-prostaglandin J2 is a selective PPARγ (EC50 of 2 µM) and a covalent PPARδ agonist. 15-Deoxy-Δ-12,14-prostaglandin J2 promotes efficient differentiation of C3H10T1/2 fibroblasts to adipocytes with an EC50 of 7 μM[1][2][3].
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15-Deoxy-Δ12,14-Prostaglandin J2-2-glyceryl ester | 15-Deoxy-Δ12,14-Prostaglandin J2-2-glyceryl ester is a derivate of 15-Deoxy-Δ-12,14-prostaglandin J2 (HY-108568). 15-Deoxy-Δ-12,14-prostaglandin J2 (15d-PGJ2) is a cyclopentenone prostaglandin and a metabolite of PGD2. 15-Deoxy-Δ-12,14-prostaglandin J2 is a selective PPARγ (EC50 of 2 µM) and a covalent PPARδ agonist. 15-Deoxy-Δ-12,14-prostaglandin J2 promotes efficient differentiation of C3H10T1/2 fibroblasts to adipocytes with an EC50 of 7 μM. | |||||||||||||||||||||
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