19492-03-6
19492-03-6
Chemical Structure
8-Hydroxy-7-methoxycoumarin
- CAS No.: 19492-03-6
- Formula:C10H8O4
- Molecular Weight:192.17
IUPAC Name: 8-hydroxy-7-methoxy-2H-chromen-2-one
InChIKey: KIGCGZUAVODHMD-UHFFFAOYSA-N
SMILES: O=C1C=CC2=CC=C(OC)C(O)=C2O1
Biological Activity: 8-Hydroxy-7-methoxycoumarin is a phenylpropanoid isolated from the calyxes of Physalis alkekengi L. var. franchetii (Mast.) Makino. 8-Hydroxy-7-methoxycoumarin shows cytotoxicity against GLC4 and COLO 320 cancer cell after continuous incubation (4 days) with IC50s of 179 μM and 145 μM[1][2].
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8-Hydroxy-7-methoxycoumarin | 8-Hydroxy-7-methoxycoumarin is a phenylpropanoid isolated from the calyxes of Physalis alkekengi L. var. franchetii (Mast.) Makino. 8-Hydroxy-7-methoxycoumarin shows cytotoxicity against GLC4 and COLO 320 cancer cell after continuous incubation (4 days) with IC50s of 179 μM and 145 μM. | |||||||||||||||||||||
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References
- [1]. HuiLv, et al. Chemical constituents from the calyxes of Physalis alkekengi L. var. franchetii (Mast.) Makino. Biochemical Systematics and Ecology, Volume 78, June 2018, Pages 63-65.
- [2]. H Kolodzie, et al. Structure-cytotoxicity relationships of a series of natural and semi-synthetic simple coumarins as assessed in two human tumour cell lines. Z Naturforsch C J Biosci. 1997 Mar-Apr;52(3-4):240-4. [Content Brief]
