194979-70-9
194979-70-9
Chemical Structure
(S)-CPP sodium
- CAS No.: 194979-70-9
- Formula:C9H8ClNaO2
- Molecular Weight:206.60
IUPAC Name: sodium (S)-2-chloro-3-phenylpropanoate
InChIKey: HMHPCHNNVOLTFC-QRPNPIFTSA-M
SMILES: O=C(O[Na])[C@@H](Cl)CC1=CC=CC=C1
Biological Activity: (S)-CPP sodium serves as an inhibitor of the branched-chain α-ketoacid dehydrogenase complex (BCKDC) kinase, commonly referred to as BDK or keto acid dehydrogenase kinase. As a negative regulator of BCKDC activity, the inhibition of BDK by (S)-CPP (with an IC50 of 6.3 μM) results in the activation of the complex and a notable decrease in plasma levels of leucine/isoleucine and valine in wild-type mice.
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(S)-CPP sodium | (S)-CPP sodium serves as an inhibitor of the branched-chain α-ketoacid dehydrogenase complex (BCKDC) kinase, commonly referred to as BDK or keto acid dehydrogenase kinase. As a negative regulator of BCKDC activity, the inhibition of BDK by (S)-CPP (with an IC50 of 6.3 μM) results in the activation of the complex and a notable decrease in plasma levels of leucine/isoleucine and valine in wild-type mice. | |||||||||||||||||||||
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