1957235-67-4

Thalidomide-NH-(CH2)2-NH2 TFA Chemical Structure
1957235-67-4

Chemical Structure

Thalidomide-NH-(CH2)2-NH2 TFA

  • CAS No.: 1957235-67-4
  • Formula:C17H17F3N4O6
  • Molecular Weight:430.34

IUPAC Name: 4-((2-aminoethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione 2,2,2-trifluoroacetate

InChIKey: OXSMNKJVQUZNEJ-UHFFFAOYSA-N

SMILES: O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3NCCN)=O.O=C(O)C(F)(F)F

Biological Activity: Thalidomide-NH-(CH2)2-NH2 TFA is an alkyl-modified Thalidomide (HY-14658) that acts as a Cereblon ligand to recruit CRBN proteins. Thalidomide-NH-(CH2)2-NH2 TFA is a key intermediate in the synthesis of CRBN-based PROTAC molecules designed to synthesize small PROTAC molecules targeting SHP2 protein.

Cat. No. Product Name Purity Description Pricing
HY-W584514
Thalidomide-NH-(CH2)2-NH2 TFA 99.38% Thalidomide-NH-(CH2)2-NH2 TFA is an alkyl-modified Thalidomide (HY-14658) that acts as a Cereblon ligand to recruit CRBN proteins. Thalidomide-NH-(CH2)2-NH2 TFA is a key intermediate in the synthesis of CRBN-based PROTAC molecules designed to synthesize small PROTAC molecules targeting SHP2 protein.
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This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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